The Simpsons finished a jigsaw puzzle and found it was missing a piece. Homer thought that the piece was in Marge's memory chest, so looked in it for the piece. Instead, he found a note saying that Marge had wanted to dump him before they got married. Heartbroken and upset, Homer moved out and went looking for another place to live. He eventually moved into Grady's and Julio's apartment in Springfield's Gay Neighborhood. Grady and Julio were a gay couple who needed a third person in their apartment as they had just had a roommate move out. They got along well with Homer, so the trio became roommates. As time went by, Grady developed feelings for Homer, eventually kissing him. Homer, however, had found out that Marge really loved him after all and moved back into his house again, leaving Grady and Julio behind. As Homer left, he ran away saying to Grady, "I'll only hurt you!"
Grady attended a party at the Simpson house to find Waylon Smithers a boyfriend.
Grady and Julio were a couple when Homer moved in with them,, but they apparently broke up some time after that as Julio was seen getting married to Thad. Julio and Thad apparently broke up later, and later still, Grady and Julio got back together.
Grady is implied to have feelings for Homer after kissing him. However, Homer didn't return those feelings and ended up running back to Marge.
Homer made Grady break up with Julio so he could date Duffman instead.
At some point he entered a relationship with Mr. Largo.