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Radioactive Man Icon.png The contents of this article or section are related to the Radioactive Man universe. They are considered fictional in The Simpsons.

Eczema are a secret evil society led by Madame Eczema.


When Madame Eczema joined Eczema, she worked her way to the top by killing her superiors.[1]

Radioactive Man fought against Eczema and the leader, Madame Eczema, revealed to the world that Radioactive Man was Claude Kane III. Radioactive Man was then killed by Eczematous-Prime.[2] It later turned out that Radioactive Man faked his death so that he could keep his identity safe.

Madame Eczema used Eczema to hold a fake seance so she could capture the Superior Squad.[3] The plan worked and Madame Eczema planned to kill the Superior Squad live on TV. However, Radioactive Man came in and rescued the Superior Squad, who took down Eczema.[4]

Black Partridge was seen fighting against Eczema as Sheldon Phillips walked by them.[5]