- For others named Molly, see Molly.
Molly is an octopus that Lisa saved and befriended whilst filming My Cephalopod Soulmate.
When Lisa was making a film underwater as part of the Future Nature Documentarians, she found Molly and decided to film her. During the film, Molly got attacked by a shark and seemingly got killed by it. However, Lisa actually saved Molly from the shark, with the shark only biting off one tentacle. Lisa then took Molly home with her, whilst she ended the film with Molly seemingly being killed because they weren't allowed to interfere with nature.
After showing off her film at the festival, Lisa and Molly started to spend time together. However, Molly liked to escape and cause trouble around the house, using the pipes to get around. This led to Lisa getting an octopus-proof tank, which Molly still managed to escape. When Lisa found Molly in Santa's Little Helper's dog bowl, she decided to take Molly to school with her to keep an eye on her.
During the school project presentation, Lisa overheard Homer talking to Bart about his crush on Ms. Peyton and heard Homer say that there are awesome things in the world that aren't meant to be his awesome thing, and that he had to let it go. This message got through to Lisa as well, who decided to let Molly go after school. During the presentation, Bart got upset about Ms. Peyton having a husband and went to yell into Molly's jar to let his feelings out. Molly then latched onto Bart's face, which caused him to fall into the switch for the bleacher seats, and then into the exercise ball shelves. This caused chaos which destroyed all the projects. Lisa then managed to get Molly off of Bart's face.
After school, Lisa let Molly out back into the ocean. When the same shark went back for Molly, Lisa grabbed the shark and threw it into another part of the ocean. When Database looked at her, Lisa told him that she was part of nature too.