Radioactive waste is commonly seen around Springfield as an ominous green sludge-like liquid, often sealed in leaking drums marked with the radioactive symbol. These barrels are commonly seen due to the lax disposal methods of the Springfield Nuclear Power Plant and Mr. Burns.
On many occasions the liquid itself can be heard humming and throbbing as if it were alive. It is seen in many unsafe dumping environments such as under the sea, stuffed into trees, hidden in playgrounds and the homes of the plant employees.
The Springfield Toxic Waste Dump is the only structured area within the town where radioactive waste can be dumped.
In The Simpsons: Hit & Run, Professor Frink learned that the invading Kang and Kodos' only weakness was nuclear waste. Mr. Burns gave Homer access to his supply of waste which was boarded onto the aliens' spaceship. The waste caused the ship to explode and killed the aliens, with the additional side effect of giving Homer a third arm. In addition, nuclear waste can be seen dripping from pipes at the Nuclear Power Plant, and in Level 4, a number of pick-up trucks that drive around the town carry barrels of waste.
Bart and Milhouse went to the power plant and exposed an ant to nuclear waste and made it bite them, hoping it would give them superpowers. Instead they were hospitalized with radiation poisoning. The ant later bit Homer, giving him a superpower in knowledge of donuts, which he utilized in a new job at the Lard Lad Donuts factory.
Victims of the waste
- Episode – "Homer's Odyssey"
- Episode – "Life on the Fast Lane" (barrel)
- Episode – "Krusty Gets Busted" (barrel)
- Episode – "Stark Raving Dad" (barrel)
- Episode – "Marge vs. the Monorail"
- Episode – "Hello Gutter, Hello Fadder"
- Episode – "The Blunder Years"
- – The Simpsons Movie
- Episode – "Bart's Not Dead"
- Comic story – The Homer Effect
- Video game – The Simpsons Road Rage
- Video game – The Simpsons Skateboarding
- Video game – The Simpsons: Hit & Run