Mr. Lisa's Opus/References
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- The title of the episode is a reference to the film Mr. Holland's Opus.
- Homer imagines Albert Einstein inventing the Led light up shoes.
- The Devil mentions Universal Studios and references the Flaming Moe drink being expensive there.
- In the song "Those Were the Days":
- The sign "Harvard College Even Our Dropouts Are Billionaires" is a reference to Bill Gates, who dropped out of Harvard to found Microsoft.
- Pictures of Presidents Franklin D. and Theodore Roosevelt, both Harvard graduates, are hanging on the wall in the Harvard Admissions Office.
- Homer sings "By the Beautiful Sea" by Harry Carroll and Harold R. Atteridge when he starts to act like Grampa.
- "Remembering You" by Roger Kellaway, the end theme for All in the Family, plays during the end credits.
- The title screen is a Christmas version of The Ned-liest Catch's.
- Lisa has a poster of the Doe-Eyed Boys on her bedroom wall. ("Friend with Benefit")
- Leon Kompowsky appears and sings new verses of "Happy Birthday, Lisa" with Bart. ("Stark Raving Dad")
- Grampa previously stated Homer stopped drinking in the future. ("Holidays of Future Passed")
- In Homer's vision, Moe brings back the Flaming Moe. ("Flaming Moe's")
- Homer and Marge sing a new version of "Those Were the Days". ("Lisa's Sax")
- When Lisa is seen as a baby, Marge's hairstyle is the one she had in That '90s Show, though she always had her hair up in a beehive since she was pregnant with Bart.