When trying to get the free beer, Barney says "Easey Barney, remember the 12 steps" before performing a gymnastic movement. The joke is that 12 Steps is the name of a program to help people recover from substance addictions, behavioral addictions, and compulsions.
After getting the free beer, Barney imitates the Road Runner from Wile E. Coyote and the Road Runner performing its iconic sound effect "Meep-meep!".
According to Homer, tourists never buy his map pointing to celebrities' homes. The map includes the name of Italian-American actress Isabella Rossellini and a potential place for a Denny's restaurant.
Moe mentions Lean Cuisine, a brand of frozen entrées and dinners.
A young Marge hangs a poster of American actor and musician David Cassidy on the wall. Cassidy was considered a teen idol back in his days.
Patty, on the other hand, hangs a poster of Miss Jane Hathaway, a recurrent character from the 1962 sitcom The Beverly Hillbillies portrayed by Nancy Kulp. Kulp came out of the closet at the age of 67 and acknowledged she was a lesbian.
An adult Marge looks at a poster of the 1993 romantic comedy Sleepless in Seattle.
Patty compares the moment she met Veronica to a scene from a Hollywood movie, to what Homer says it was Bride of the Monster, a 1955 sci-fi horror film.
Disco Stu got an annulment from Pope John Paul II for his marriage with Selma. John Paul II died just a few days after this episode aired.
Marge finds out Veronica is a man when she sees that the toilet seat is up. The same thing happens in the 1993 comedy Mrs. Doubtfire when Christopher Hillard (Matthew Lawrence) finds out Mrs. Doubtfire (Robin Williams) is a man when he catches him standing up to pee.
Because of the controversy over gay marriage in the United States, this episode had a Parental Discretion Advised warning before the show, the first (and so far, only) time for The Simpsons and it was rated TV-14 DLV, the sixth time for The Simpsons.
This episode was given a PG rating with an "Adult Themes" advisory in Australia.
Although Homer stopped being homophobic in "Homer's Phobia" and even lived together with two openly homosexual men in "Three Gays of the Condo", he still can be seen holding a sign "Death before gay marriage".
Reverend Lovejoy is unable to cite the book in the Bible condemning homosexuality (allegedly Genesis, Leviticus and others), yet in "Homer the Heretic", he is able to cite a completely random Bible verse of Homer's choosing from memory (Matthew 21:17).