At the beginning of the episode, the bed folds in half completely, parodying The Jetsons Movie, in which the scene is the method of waking up George on his first day at the Orbiting Ore Asteroid.
Dr. Hibbert refers to the American comedian Sinbad and his twisted marriage history. Sinbad got divorced in 1992 and got married again to the same woman in 2002.
Crowley asked for the direction to Mecca, known as the Qibla, which is used by Muslims to pray. He later says he was joking, as he was Jewish.
Dr. Steve accuses Homer of stealing his clients, and Homer compares that to when the American Medical Association (AMA) deprived chiropractors in 1987 to have access to the Association.
The sequence where Homer runs after the chiropractor parodies the movie Chinatown. The phrase by Moe, "Forget it Homer, it's Chiro-town", parodies the last line of the movie, "Forget it Jake, it's Chinatown".
Skinner ironically thanks comedian Bruce Vilanch for a joke that had no success. Vilanch, who was among the public, says that "Whoopie would've made it work", referring to Whoopi Goldberg, who worked with him on Hollywood Squares for four years.
Bruce Vilanch is wearing a T-shirt with the face of Fred from The Flintstones.
Chief Wiggum tells Jack Crowley that he likes to watch Oz, an HBO-produced prison drama. Wiggum also enjoys watching Sex and the City, also from HBO. Crowley mentions he likes SportsCenter. Finally, Wiggum asks Crowley if people from the mob were like The Sopranos.
Sideshow Bob can be seen in the infirmary, wearing a cast that covers him from the neck up.
Whilst working at the prison, Marge informs Bart that Sideshow Bob will be seeing him very soon. Bart laughs and replies with "Oh, that Bob". Bob would return to terrorize Bart three episode later in "Day of the Jackanapes".
Marge apparently makes horrible sundaes, as both Jack Crowley and Bart look pained when Marge urges them to eat one.