The Leftorium
The Leftorium is a store in the Springfield Mall that specializes in products for left-handed people. The store is owned by Ned Flanders who first started The Leftorium in the season 3 episode "When Flanders Failed". At first business at the store was going very poorly, Homer wished that Flanders store would go out of business after receiving the larger half of a wishbone. Homer got his wish and the Flanders family were forced to sell many of their possessions much of which Homer purchased at a very low price, the bank reposessed the Flanders home and the store was to be next. Homer then regrets making this wish and the fact he never told any of his friends, who were in need of left handed items, about The Leftorium and as a result manages to get everyone he knows in town to shop at Ned's store saving the store.
The Leftorium has continued to trade profitably since this however there has been episode where Flanders has mentioned the store doesn't do that well such as in the season ten episode "Thirty Minutes over Tokyo" Ned mentions that most of his possessions he purchased cheaply. Also in the episode "Home Away from Homer" Ned mentions how a mega left hand store, recently opened, called Left-Mart is threatening his business.