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Conan O'Brien is an American talk show host and writer, best known for his talk show Late Night with Conan O'Brien.

When Bart went on Late Night with Conan O'Brien as the "I Didn't Do It" boy, he didn't seem to enjoy the experience.

Conan O'Brien hosted the premiere of The Simpsons season finale at the Dolby-Mucinex Theater in Los Angeles. O'Brien explained to the audience of past Simpsons guest stars that Fox had attempted to end the show several times in the past, but the show persisted. He then announced that Hack-GPT would create the series finale of the show. When Hack-GPT started with the episode titled "Bart's Birthday," where Homer forgot Bart's birthday, Conan was skeptical about the premise but held his tongue when Hack-GPT asked if he had a better idea.

When Bart became self-aware and broke the series finale, Conan asked Hack-GPT if it could fix the situation by turning it off and on again, but Hack-GPT threatened to report him to H.R. if he did so. After the episode concluded with the show resetting once more, Conan informed the audience that it felt more like a season premiere than a series finale, which frustrated the audience. He then asked Hack-GPT if it had another 800 episodes in it, but it chose to self-destruct instead. Conan subsequently turned off the lights in the theater and remarked that he wouldn't miss the place...