Peyton Manning

Peyton Manning is the quarterback for the Indianapolis Colts and the older brother of Eli Manning and the younger brother of Cooper Manning. He appears with his brothers in the episode "O Brother, Where Bart Thou?".

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Guest stars in season 21

Seth Rogen • Kevin Michael Richardson • Matt Groening • Chuck Liddell • Jonah Hill • Neve Campbell • Smothers Brothers (Dick Smothers • Tom Smothers) • Peyton Manning • Eli Manning • Cooper Manning • Kim Cattrall • Huell Howser • Jordan Nagai • Mitch Albom • Anne Hathaway • Gary Larson • Eartha Kitt • Jackie Mason • Chris Martin • Bob Costas • Wren T. Brown • Sarah Silverman • Angela Bassett • Sacha Baron Cohen • Yael Naim • Joe Mantegna • Jane Kaczmarek • Maurice LaMarche • Eddie Izzard • Don Pardo • Kelsey Grammer • Ryan Seacrest • Randy Jackson • Ellen DeGeneres • Kara DioGuardi • Simon Cowell • Rupert Murdoch