Little Big Mom/References

Cultural references

 * The episode title is a pun on the film .
 * The Virtual Doctor website says that it's from the creators of ' and SimSandwich. Dragon Quest is a series of RPGs released by (originally released as Dragon Warrior in the US). SimSandwich is a reference to the Sim series of games, the most famous of which is '.
 * In the hospital, Homer and Bart squirt at each other.
 * I Love Lucy references:
 * Homer and Bart watch an episode of the show.
 * Lisa meets the ghost of Lucy McGillicuddy Ricardo Carmichael, who gives her an idea for how to get even with Homer and Bart for their laziness. Ghost Lucy's surnames refer to characters that Lucille Ball portrayed on I Love Lucy and .
 * After telling Lisa her name, Ghost Lucy says, "And I think there's some more", an offhand reference to Lucy Carter, Ball's character on '; and to Lucy Barker, her character on '.
 * During the Itchy & Scratchy cartoon ("The Tears of a Clone"), the Scratchy clones emerge from the cloning machine faster than Itchy can kill them, a reference to the candy wrapping scene from the I Love Lucy episode "Job Switching".
 * At the very end of the episode, Homer sings "" between screams while he receives a needle treatment.

Trivia

 * This is the first episode to air during the 2000s.
 * During The Itchy & Scratchy Show cartoon, the pictures Itchy looks at in his photo album are from previous I&S cartoons (see "Tears of a Clone").
 * Lisa says "Excellent!" in the same way as Mr. Burns.

Goofs

 * When Marge rushes through the door at the start of the episode, she opens to the inside, but when she is outside, she nails a wedge to the underside of the door. This wouldn't work, since the door opens the other way, but the Simpson family tries to open it outwards.
 * The clock falls on Marge's LEFT leg, yet it breaks her right leg.

Continuity

 * The snowboarding lingo "blast a dookie" also appears in the comic story Otto's Gnarly Snowboarder's Glossary.