Doctor Octopus

Otto Octavius, better known as Doctor Octopus is a Marvel super villain and an enemy of Spider-Man.

History
At Nelson's birthday party played him and Bart with an actor that played Dr. Octopus.

When Lisa finds Dr. Nick in the cemetery, he puts four severed arms around his body and says: "I'm not Dr. Nick, I am Dr. Octopus!".

He appeared on the cover of The Awesome Spider-Man and was getting married to Mary Jane Watson. Peter Parker was the photographer of the wedding.

Comic Book Guy was dressed as him at Bi-Mon-Sci-Fi-Con in 2004.

Behind the Laughter

 * Though depicted with blond hair in "Married to the Blob", in the comics Doctor Octopus has brown hair.