Spider-Man

Spider-Man is a Marvel superhero.

History
The opening of the film Gladys the Groovy Mule parodies the opening of the original Spider-Man story from Amazing Fantasy #15. Several analogues include Peter Lewis (reference to Peter Parker), Gwen (reference to Gwen Stacy in name and Liz Allen in behaviour) and Bash Flashman (reference to Flash Thompson).

He was in the video Krusty on the Electric Company. He comes in and starts dancing when Krusty gets hit on the head by a stage-light.

In the montage of kisses when Nikki performed CPR on Bart there was a scene where Spider-Man and Mary Jane Watson are kissing.

Bart mentioned that Disney created Spider-Man.

Non-canon
In the origin of Fallout Boy, it's revealed that a radioactive spider was about to bite Rod Runtledge until it was flicked away by Claude Kane III onto the hand of Peter Parker.

Peter Griffin took a photo of Spider-Man when he was trying to take a photo of a woman's thong. He then sold this photo to J. Jonah Jameson who then owed Peter a favor.