The Fly

The Fly is a 1958 science fiction horror movie by Kurt Neumann based on a short story by George Langelaan. The plot follows a scientist who accidentally mutates himself into a fly. One version of himself has a fly's head and paw but an otherwise human body, the other has the body of a fly with his head. The picture also had Vincent Price in a supporting role. In 1986 the film was remade by David Cronenberg starring Jeff Goldblum and Geena Davis. Both films have been frequently referenced on The Simpsons.

References to The Fly in The Simpsons books
Comic Book Guy's Book of Pop Culture Comic Book Guy cites Veronica Quaife's quote, "Be afraid. Be very afraid" as one of the "Greatest Quotes of All Time".